Haoyun Lei

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PhD Student in Joint Carnegie Mellon/University of Pittsburgh Ph.D. Programming in Computational Biology (CPCB)
Dr. Schwartz Lab
Computational Biology Department
School of Computer Science
Carnegie Mellon University

Advisor: Professor Russell Schwartz

About me

I am currently a fifth-year Ph.D. student in Computational Biology at Carnegie Mellon University. I got my B.S. degree in Biological Science from Huazhong University of Science and Technology in 2012. I spent three years working as a research scholar in University of Michigan, investigated the neuron mechanism in Caenorhabditis elegans. Then I started my research in Computational Biology.

Research

My research goal is mainly to design algorithms to combine multiple types of genomic data such as bulk tumor sequencing, single-cell sequencing, fluorescent in situ hybridization data to study the tumor heterogeneity and infer accurate genomic profiles such as single nucleotide variants (SNVs), copy number variations (CNVs) and structural variants (SVs) in the important clones during tumor evolution. This inference can help to study and predict cancer progress. Also, I am interested in Computer Vision and Natural Language Processing since I realized that tumor imaging and doctor diagonsis notes are very helpful in predicting and classifying cancers.

My interests lie in

  • Bulk Tumor Deconvolution

  • Tumor Phylogenetic Tree Construction

  • Machine Learning

  • Deep Learning

  • Combinatorial Optimization

  • Mixed Linear Programming

  • Non-convex Optimization

  • Computer Vision

  • Natural Language processing

  • Feature Detection and Extraction

  • Classification and Clustering

Contact

654F, Mellon Institute, Carnegie Mellon University, Pittsburgh, PA, 15213
Email: haoyunl[@]andrew[DOT]cmu[DOT]edu (school)
leovam171[@]gmail[DOT]com (personal)

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